Энтеровирусные инфекции: современные представления об этиологии, эпидемиологии, подходы к диагностике и лечению энтеровирусных экзантем у детей
DOI:
https://doi.org/10.15574/SP.2017.84.29Ключевые слова:
энтеровирусная инфекция, дети, экзантема, лечениеАннотация
Показана роль энтеровирусной инфекции в заболеваемости населения планеты. Значительный полиморфизм клинических проявлений, отсутствие четкой зависимости от серологического типа возбудителя, частые бессимптомные формы, длительное вирусоносительство, отсутствие специфических методов профилактики делают энтеровирусную инфекцию неконтролированной болезнью. Вероятность развития у детей тяжелых и осложненных форм энтеровирусной инфекции с поражением нервной системы требует поиска путей этиопатогенетического лечения болезни.
Библиографические ссылки
Abaturov AE. (2012). Kationnyie antimikrobnyie peptidyi sistemyi nespetsificheskoy zaschityi respiratornogo trakta: defenzinyi i katelitsidinyi. Defenzinyi — molekulyi, perezhivayuschie renessans. Chast 4. Zdorove rebenka. 2: 154—160.
Almisheva ASh. (2008). Epidemiologicheskie i ekologicheskie aspektyi seroznyih meningitov enterovirusnoy prirodyi. Avtoref dis … kand med nauk. Moskva: 23.
Bogodelnikov IV. (2013). Differentsialnyiy dignoz infektsionnyih bolezney u detey. Donetsk, Zaslavskiy A.Yu.: 160—247.
Bortnikova VV. (2011). Eksperimentalnoe izuchenie bezopasnosti giporamina — novogo fitopreparata protivovirusnogo deystviya. Biomeditsina. 3: 106—108.
Demina AV, Shteynberg AV. (2009). Enterovirusyi. Chast 2. Enterovirusnyie infektsii: mnogoobrazie klinicheskih proyavleniy. Byulleten SO RAMN. 6(140): 116—125.
Doan SI. (2006). Epidemiolohichnyi analiz zakhvoriuvanosti na enterovirusni infektsii z urakhuvanniam klinichnykh proiaviv, vikovoho i terytorialnoho rozpodilu. Zaporozhskyi med zhurn. 2: 62—67.
Ershova IB. (2014). Effektivnost giporamina (Erebra) v lechenii i profilaktiki virusnyih zabolevaniy u detey. Zdorove rebenka. 8: 110—113.
Kishkurno EP, Amvroseva TV. (2007). Enterovirusnaya infektsiya u detey: klinika, diagnostika, podhodyi k terapii. Meditsina neotlozhnyih sostoyaniy. 2(9): 24—32.
Kozhevnikova NV, Karavyanskaya TN, Golubeva EB. (2007). Vozrastanie roli enterovirusov v sovremennoy infektsionnoy patologi. Dalnevostochnyiy zhurn infektsionnoy patol. 10: 52—53.
Kramarev SA, Vigovskaya OV. (2016). Innovations in the treatment and prevention of acute respiratory viral infections in children. Sovremennaya pediatriya. 1(73): 75—81.
Grebova LP, Kryigina TV, Fokicheva NN et al. (2005). Letnyaya vspyishka meningita u detey v Ryazanskoy oblasti. Aktualnyie voprosyi infektsionnoy patologii i vaktsinoprofilaktiki. Materialyi kongr: 58.
Onischenko GG, Efimov EI, Novikova NA et al. (2006). Lokalnaya vspyishka enterovirusnoy infektsii sredi shkolnikov v Nizhnem Novgorode. Epidemiologiya i infektsionnyie bolezni. 3: 12—15.
Marri D. (2006). Infektsionnyie bolezni u detey. Moskva, Praktika: 927.
Mihaylov EV, Shteynberg AV, Eremeeva IG. (2008). Meningityi enterovirusnoy etiologii u detey. Sovremennyie podhodyi k diagnostike i osobennosti klinicheskogo techeniya. Infektsionnyie bol. 6(1): 31—34.
Herasymov SV, Bielova HA, Pavuk HL et al. (2014). Novi pidkhody do likuvannia hostroi respiratornoi virusnoi infektsii u ditei. Sovremennaya pediatriya. 4(60): 111—114.
Pro zatverdzhennia Protokoliv diahnostyky ta likuvannia infektsiinykh khvorob u ditei. Nakaz MOZ Ukrainy No. 354 vid 09.07.2004. http://www.moz.gov.ua.
Kriuchko TO, Kushnereva TV, Ostapenko VP et al. (2014). Problemni pytannia ambulatornoho vedennia ditei z hostrymy respiratornymy virusnymy infektsiiamy. Sovremennaya pediatriya. 8(64): 65—68.
Demina AV, Ternovoy VA, Norder H, Netesov SV. (2011). Sluchay enterovirusnoy ekzantemyi polosti rta i konechnostey, vyizvannyiy virusom Coxsackie A6. Epidemiologiya i infektsionnyie bol. 3: 23—26.
Schukina AP, Kosintseva UP. (2006). Kliniko-immunologicheskaya harakteristika seroznyih meningitov enterovirusnoy etiologii. Vestnik Ros gos med un-ta. 2: 312.
Enterovirusnyie zabolevaniya: klinika, laboratornaya diagnostika, epidemiologiya, profilaktika. Metodicheskie ukazaniya (MU 3.1.1.2130-06). Moskva, 2006.
Terletskain-Ladwig E, Metzger Ch, Schalasta G et al. (2000). A new enzyme immunoassay of enteroviruses in faecal specimens. J Med Virol. 60; 4: 439—445. https://doi.org/10.1002/(SICI)1096-9071(200004)60:4<439::AID-JMV12>3.3.CO;2-P; https://doi.org/10.1002/(SICI)1096-9071(200004)60:4<439::AID-JMV12>3.0.CO;2-Y
Arimboor R, Arumughan C. (2012). Effect of polymerization on antioxidant and xanthine oxidase inhibitory potential of sea buckthorn (H. rhamnoides) proanthocyanidins. J Food Sci. 77(10): 1036—41. http://www.ncbi.nim.nih.gov/pubmed/22938149. https://doi.org/10.1111/j.1750-3841.2012.02884.x; PMid:22938149
Liu Y, Zhang F, Fu C et al. (2015, Feb 8). Combination of intratypic and intertypic recombinant events in EV71: a novel evidence for the «triple-recombinant» strains of genotype A viruses in Mainland China from 2008 to 2010. Virus Genes.
Papadakis G, Chibo D, Druce J et al. (2014, Jan 29). Detection and genotyping of enteroviruses in cerebrospinal fluid in patients in Victoria, Australia, 2007—2013. J Med Virol. https://doi.org/10.1002/jmv.23885. Epub ahead of print.
Song Y, Cheng X, Yang X et al. (2015, Feb 24). Early growth response-1 facilitates enterovirus 71 replication by direct binding to the viral genome RNA. J Biochem Cell Biol. pii: S1357-2725(15)00055-2. doi 10.1016/j.biocel.2015.02.012. Epub ahead of print.
El Hiar R, Haddas S, Jadane H et al. (2012). Enteroviral central nervous system infections in children of the region of monastir, Tunisia: diagnosis, laboratory findings of cerebrospinal fluid and clinical manifestations. Indian J Virol. 23(3): 294—302. https://doi.org/10.1007/s13337-012-0104-1; PMid:24293816 PMCid:PMC3550789
Lashkevich VA, Koroleva GF, Lukashev AN et al. (2011). Enterovirus 71: HFMD-like disease, encephalomyelitis, acute pulmonary edema Epidemiology. Infect Bol. 6: 38—47.
Saeed M, Zaidi S, Naeem A et al. (2007). Epidemiology and clinical findings associated with enteroviral acute flaccid paralysis in Pakistan. BMC Infect Dis. 7: 49. https://doi.org/10.1186/1471-2334-7-6; PMid:17300736 PMCid:PMC1804272
March B, Eastwood K, Wright IM et al. (2013, Dec 23). Epidemiology of enteroviral meningoencephalitis in neonates and young infants. J Paediatr Child Health. https://doi.org/10.1111/jpc.12468. Epub ahead of print.
Gimferrer L, Campins M, Codina MG et al. (2015, Feb 27). First Enterovirus D68 (EV-D68) cases detected in hospitalised patients in a tertiary care university hospital in Spain, October 2014. Enferm Infecc Microbiol Clin. pii: S0213-005X(15)00051—8. doi 10.1016/j.eimc.2015.01.008. Epub ahead of print.
Mizuta K, Abiko C, Murata T et al. (2005). Frequent importation of enterovirus 71 from surrounding countries into the local community of Yamagata, Japan, between 1998 and 2003. J Clin Microbiol. 43; 12: 9171—9175. https://doi.org/10.1128/JCM.43.12.6171-6175.2005; PMid:16333123 PMCid:PMC1317214
Hosoya M, Kawasaki Y, Sata M et al. (2007). Genetic diversity of coxsachievirusї A16< associated with hand-fool-mouth disease epidemics in Japan from 1983 to 2003. J Clin Microbiol. 45; 1: 112120.
Handbook of non-invasive methods and the skin. Edited by Jшrgen Serup, Gregor BE Jemec, Gary L Grove. (2005). 2nd ed.p.
Jayashankar B, Mishra KP, Ganju L. (2014). Supercritical extract of Seabuckthorn Leaves (SCE200ET) inhibited endotoxemia by reducing inflammatory cytokines and nitric oxide synthase 2 expression. Int Immunopharmacol. 20(1): 89-94. http://www.ncbi.nim.nih.gov/pubmed/2459-4274/.https://doi.org/10.1016/j.intimp.2014.02.022; PMid:24594274
Michaylova EV, Eremeeva IG, Korhenevich AV. (2005). The clinic-laboratory characteristics of children enterovirus meningitis. 4th World Congress of the World Society for Pediatric Infectius Diseases (WSPID). Warsaw, Poland: 106.
Junttila N, Levcque N, Kabue JP et al. (2007). New enteroviruses, EV 93 and EV-94, associated with acute flaccid5paralysis in Democratic Republic of the Congo. J of Medical Virology. 79: 393-400. https://doi.org/10.1002/jmv.20825; PMid:17311342
Mavrouli MD, Spanakis N, Levidiotou S et al. (2007). Serologic prevalence of coxsackievirus group B in Greece. Viral Immunol. 20; 1: 11—18. https://doi.org/10.1089/vim.2006.0085; PMid:17425417
