Значение интерстициальных клеток кахаля в функции мочевого пузыря: современное состояние вопроса

Авторы

  • D. V. Shevchuk Житомирская областная детская клиническая больница, Украина Житомирский государственный университет имени И. Франко, Украина Национальная медицинская академия последипломного образования имени П.Л. Шупика, г. Киев, Украина, Ukraine https://orcid.org/0000-0002-3466-3430

DOI:

https://doi.org/10.15574/10.15574/SP.2017.81.117

Ключевые слова:

интерстициальные клетки Кахаля, нервно-мышечная дисфункция мочевого пузыря

Аннотация

Интерстициальные клетки Кахаля (ИКК) впервые были открыты в 1893 году в стенке кишечника и лишь спустя почти 100 лет интерес к ИКК возобновился. Кроме того, современные технологии дали возможность выявить схожие клетки и в других органах, в частности тех, которые содержат мышечные волокна и, соответственно, подлежат сокращению. Так, ИКК были обнаружены в мочевых путях, фаллопиевых трубах, семенных канальцах и т.д. Дальнейшее исследование функции ИКК установило связь между нарушением периферической иннервации мочевого пузыря (нервно-мышечная дисфункция мочевого пузыря) и концентрацией ИКК. Таким образом, исследование концентрации ИКК в стенке мочевого пузыря при его дисфункции может повлиять на тактику ведения больных в перспективе.

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Раздел

Заболевания органов мочевыделительной системы