Множественная антибактериальная резистентность Streptococcus pneumoniaе. Возможности эмпирической антибактериальной терапия пневмококковой инфекции у детей
DOI:
https://doi.org/10.15574/SP.2015.69.49Аннотация
Определен уровень резистентности к антимикробным препаратам S. pneumoniaе, выделенных из носоглотки здоровых детей до 5 лет (n=180). Выявлен высокий уровень мультирезистентности (35,0%). Предложены рекомендации по рациональной антибиотикотерапии пневмококковой инфекции, основанные на локальных данных.
Ключевые слова: S. pneumoniae, назофарингеальне носительство, резистентность, антимикробные препараты.
Библиографические ссылки
Feshchenko YuI, Dziublyk OIa, Pertseva TO ta in. 2014. Doslidzhennia antybiotykorezystentnosti shtamiv S.pneumoniae ta H. influenzae, vydilenykh vid khvorykh iz nehospitalnymy infektsiiamy dykhalnykh shliakhiv u 2010—2012 rr. v Ukraini. Visn morfol. 20;2: 395—401.
Kozlov RS. 2004. Puti optimizatsii monitoringa, profilaktiki i farmakoterapii pnevmokokkovyih infektsiy. Avtoref dis d-ra med nauk. 14.00.25, 03.00.07. Smolensk: 44.
Lezhenko GA, Pashkova EE, Pantyushenko LI. 2013. Rational antibacterial therapy of respiratory diseases in children. Sovremennaya pediatriya. 7(55): 88—92.
Stovban MP, Ostrovskyi MM, Stovban IV, Savelikhina IO. 2008. Otsinka stanu problemy pnevmokokovykh infektsii: epidemiolohiia, diahnostyka, rozvytok rezystentnosti do antybiotykiv ta yii profilaktyka. Arkh klin medytsyny. 1(13): 15—18.
Pro zatverdzhennia metodychnykh vkazivok «Vyznachennia chutlyvosti mikroorhanizmiv do antybakterialnykh preparativ». Nakaz MOZ Ukrainy № 167 vid 05.04.2007 r. http://www.moz.gov.ua.
Feshchenko Y, Dzyublik F, Pertseva T et al. 2014. Antibacterial resistance among Streptococcus pneumonia and Haemophilus influenza from Ukraine Results from the Survey of Antibiotic Resistance (SOAR) 2011—2013. Poster presentation (P-1589) 24th ECCMID. Barselona, Spain. PMid:25823339
Bean DC, Klena JD. 2005. Characterization of major clones of antibiotic-resistant Streptococcus pneumoniae in New Zealand by multilocus sequence typing. J Antimicrob Chemother. 55: 375—8. Epub 2005 Jan 28. http://dx.doi.org/10.1093/jac/dki001; PMid:15681581
Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing; twenty third informational supplement. CLSI document M100-S23. 2013. 33;1: 104—109.
Rahman M, Hossain S, Shoma S et al. 2006. Emergence of a unique multiply-antibiotic-resistant Streptococcus pneumoniae serotype 7B clone in Dhaka, Bangladesh. Journal of Clinical Microbiology. 44: 4625—4627. http://dx.doi.org/10.1128/JCM.01740-06; PMid:17005734 PMCid:PMC1698382
European Centre for Disease Prevention and Control. Annual Epidemiological Report on Communicable Diseases in Europe 2010. — Stockholm : ECDC, 2010.
European Committee on Antimicrobial Susceptibility Testing Breakpoint tables for interpretation of MICs and zone diameters. Version 1.3. 2011, January 5.
Whitney CG, Farley MM, Hadler J et al. 2000. Increasing prevalence of multidrug-resistant Streptococcus pneumoniae in the United States. The New England Journal of Medicine. 343: 1917—24. http://dx.doi.org/10.1056/NEJM200012283432603; PMid:11136262
Metlay JP, Branas CC, Fishman NO. 2004. Hospital-reported pneumococcal susceptibility to penicillin. Emerging Infectious Diseases. 10: 54—59. http://dx.doi.org/10.3201/eid1001.030140; PMid:15078597 PMCid:PMC3322741
Bayraktar MR, Durmaza B, Kalcioglu MT et al. 2005. Nasopharyngeal carriage, antimicrobial susceptibility, serotype distribution and clonal relatedness of Streptococcus pneumoniae isolates in healthy children in Malatya, Turkey. International Journal of Antimicrobial Agents. 26: 241—246. http://dx.doi.org/10.1016/j.ijantimicag.2005.06.014; PMid:16118046
Mosca A, Carucci A, Santacroce L, Schettini F et al. 2003. Streptococcus pneumoniae nasopharyngeal colonization in young healthy children: rate of carriage, serotype distribution, and antibiotic resistance. New Microbiol. 26: 187—192. PMid:12737202
Jones ME, Blosser-Middleton RS, Thornsberry C et al. 2003. The activity of levofloxacin and other antimicrobials against clinical isolates of Streptococcus pneumoniae collected worldwide during 1999—2002. Diagnostic Microbiology and Infectious Disease. 47: 579—86. http://dx.doi.org/10.1016/S0732-8893(03)00140-8
Vilhelmsson SE, Tomasz A, Kristinsson KG. 2000. Molecular evolution in a multidrug-resistant lineage of Streptococcus pneumoniae: emergence of strains belonging to the serotype 6B Icelandic clone that lost antibiotic resistance traits. Journal of Clinical Microbiology. 38: 1375—1381. PMid:10747110 PMCid:PMC86448
